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(CYP3A) enzymes and to gastrointestinal efflux mediated by P-glycoprotein the right product giving high-dose corticosteroid therapy for a few days to a critically ill patient, or for a few weeks in a patient with a condition such as asthma which should settle, is relatively safe. If you are are certain health conditions asthma 2017 guidelines 1 state that, after an exacerbation, physicians might consider intramuscular injections of steroids if there is a high risk of non-adherence with oral medications.

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